Steroids and derivatives
Medchemexpress LLC 1-Methylguanosine-d3 | 2140-65-0 | 99.5% | 300.29 | 1 MG
1-Methylguanosine-d3 (N1-Methylguanosine-d3) is a deuterium labeled form of 1-Methylguanosine, a methylated nucleoside derived from RNA degradation and identified as a tumour marker. This compound is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC HY-A0020 1mg Medchemexpress, Eldecalcitol CAS:104121-92-8 Purity:>98%
Medchemexpress, HY-A0020 1mg Eldecalcitol CAS:104121-92-8 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Prostaglandin D2 | 41598-07-6 | MFCD00077857 | 99.5% | 352.47 | C20H32O5 | 1 MG
Prostaglandin D2 (PGD2) is an endogenous eicosanoid involved in sleep regulation and immune/inflammatory signaling. Supplied as a research reagent, this purified compound is intended for in vitro and biochemical studies and is accompanied by safety and analytical documentation for laboratory use.
- High purity (99.5%) suitable for analytical and pharmacological experiments.
- Molecular weight 352.47 and chemical formula C20H32O5.
- Available in small milligram pack sizes for bench-scale research.
- Accompanied by SDS and certificate of analysis to support safe handling and data traceability.
- Commonly used in studies of sleep, inflammation, and prostaglandin signaling pathways.
Sigma Aldrich Fine Chemicals Biosciences 1alpha,25-Dihydroxyvitamin D3 >=97.0% (HPLC) | 32222-06-3 | MFCD00867079 | 1MG
1alpha,25-Dihydroxyvitamin D3 >=97.0% (HPLC) | Purity: >=97.0% (HPLC) | Mol Wt: 416.64 | 32222-06-3 | MFCD00867079 | 1MG
Medchemexpress LLC Estradiol (Standard) | 50-28-2 | MFCD00003693 | 99.98% | 100 MG
Estradiol (Standard) is the analytical standard of Estradiol, a steroid hormone and the major female sex hormone. This compound can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. It is used in research for cancers, neurodegenerative diseases, and neural tissue engineering.
- Used as a reference standard for assays
- Utilized in qualitative, quantitative, and methodological research experiments
- Promotes neural differentiation of human endometrial stem cells
- Supports research in cancers, neurodegenerative diseases, and neural tissue engineering
- Commonly used in HPLC, GC, and MS applications
Apexbio Technology LLC α-Estradiol 57-91-0 50mg
alpha-Estradiol (57-91-0) is a small-molecule inhibitor targeting 5 -reductase the enzyme responsible for converting testosterone to dihydrotestosterone (DHT) It is designed to inhibit 5 -reductase activity thereby modulating androgen metabolism and androgen-related signaling pathways alpha-Estradiol exerts its biological activity primarily through enzyme inhibition In reported experimental studies alpha-Estradiol demonstrates inhibitory activity against 5 -reductase with an IC50 value ranging from approximately 1 to 10 M though the precise value may depend on assay conditions Based on these pharmacological properties alpha-Estradiol holds research potential in the treatment and study of androgenetic alopecia
eMolecules 79037-37-9 | Medchem Express | Estradiol-d3 | 1mg | 713707131 | HY-B0141S | MFCD01074033 | 275.406 | C18H24O2
Medchem Express | Estradiol-d3 | 1mg | 713707131 | HY-B0141S | 79037-37-9 | MFCD01074033 | 275.406 | C18H24O2
Apexbio Technology LLC Ethinyl Estradiol 57-63-6 10mM (in 1mL DMSO)
Ethinyl Estradiol (57-63-6) is a small-molecule estrogen receptor agonist targeting intracellular estrogen receptors It is designed to activate these receptors thereby regulating transcription of estrogen-responsive genes and influencing reproductive biology and cell proliferation pathways Ethinyl Estradiol exerts its biological activity primarily through direct binding to estrogen receptors leading to the modulation of endocrine-regulated mechanisms Based on these pharmacological properties Ethinyl Estradiol holds research potential in studies of receptor-mediated responses endocrine regulation mechanisms synthetic hormone interactions drug interactions contraceptive mechanisms and hormone-dependent physiological processes
Medchemexpress LLC Alpha-Estradiol | 57-91-0 | 99.9% | 5 G
Alpha-Estradiol is identified as a weak estrogen and a 5α-reductase inhibitor. It is employed as a topical medication for treating androgenic alopecia.
- Weak estrogen.
- Acts as a 5α-reductase inhibitor, preventing testosterone metabolism catalyzed by 5 alpha-reductase.
- Attenuates LPS-induced inflammatory markers in mouse embryonic fibroblast (MEF) cells, primary pre-adipocytes, and differentiated 3T3-L1 adipocytes through an ERα-dependent mechanism.
- Decreases NFκB-p65 and elevates ERα protein expression.
- Significantly reduces the central avascular/total retina area in mouse pups.
- Lowers malondialdehyde (MDA) levels, the number of NADPH-oxidase-positive cells, NADPH oxidase concentration, and activity in the retinas of hyperoxia-exposed pups.
Medchemexpress LLC Estra-1,3,5(10)-triene-3,17-diol, (17α)- | 57-91-0 | 99.46% | 1 ML
Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor, known for its use as a topical medication in the treatment of androgenic alopecia. This compound inhibits testosterone metabolism and attenuates LPS-induced inflammatory markers.
- Weak estrogen and 5α-reductase inhibitor
- Inhibits testosterone metabolism
- Attenuates LPS-induced inflammatory markers
- Molecular weight: 272.39
- Chemical formula: C18H24O2
- Appearance: White to off-white solid
- For research use only
Medchemexpress LLC Estradiol 17-(β-D-glucuronide) sodium | 15087-02-2 | MFCD00056557 | 99.5% | C24H31NaO8 | 10MG
Estradiol 17-(β-D-glucuronide) sodium is the sodium salt of a conjugated estrogen (E217G) formed in the liver and excreted in bile. It is used as a research reagent to investigate estrogen metabolism, transporter activity, and mechanisms of cholestasis. Supplied as a high-purity solid for in vitro and biochemical assays; for research use only.
- High purity suitable for analytical and biochemical assays.
- Serves as a substrate for hepatic transporters involved in bile excretion.
- Relevant for studying intrahepatic cholestasis and estrogen metabolism.
- Soluble in polar organic solvents such as DMSO and DMF.
- Available in multiple small-scale pack sizes for lab use.
Medchemexpress LLC Alpha-Estradiol (Standard) | 57-91-0 | 99.9% | 50 MG
Alpha-Estradiol (Standard) is the analytical standard of Alpha-Estradiol, intended for research and analytical applications. Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor used as a topical medication in the treatment of androgenic alopecia.
- Analytical standard for research and analytical applications
- Used in HPLC, GC, and MS experiments
- Weak estrogen and 5α-reductase inhibitor
- Solid appearance, white to off-white
- Stable under recommended storage conditions
FUJIFILM BIOSCIENCES INC Digitonin
Digitonin is a spirostan saponin obtained from the seeds and leaves of digitalis D purpurea D lanata A mild nonionic detergent digitonin is used in a wide range of applications including solubilization of membrane proteins permeabilization of cellular membranes isolation of mitochondria and quantitation of cholesterol Water Soluble 4% For research use only RUO